The Science Behind MonaLean™ Ingredients: How GLP-1 Booster™ Supports Blood Sugar, Appetite Control, and Fat Loss

MonaLean™ by Theramone Health™ is thoughtfully crafted to stimulate your body’s natural production of GLP-1 hormone, improve its biological activity, and enhance responsiveness to this key metabolic hormone. These actions support:

  • Healthy blood glucose regulation
  • Suppressed appetite and cravings
  • Reduction in body fat and improved body composition*

Backed by science and powered by nature, MonaLean™ features patent-pending GLP-1 signaling technology and is made from plant-based, clinically validated ingredients. Together, they deliver measurable metabolic health benefits—naturally and safely.


🌿 Plant-Based Ingredients with Proven Metabolic Benefits


Green Tea Leaf Extract (Camellia sinensis)

Rich in epigallocatechin gallate (EGCG), green tea extract is widely studied for its glucose and weight management effects. It’s been shown to:

  • Stimulate natural GLP-1 hormone production
  • Support insulin sensitivity[8]
  • Reduce blood glucose levels[8]
  • Suppress appetite and cravings[8]
  • Promote fat loss and weight reduction*

🧪 Clinical studies [1,2] show green tea extract helps reduce waist circumference, LDL cholesterol, and total body weight, particularly in women with central obesity—through ghrelin inhibition, increased adiponectin, and improved GLP-1 signaling.*


Berberine (from Berberis aristata bark)

Berberine is a powerhouse botanical compound with multiple metabolic effects* [3,4,5]:

  • Increases GLP-1 secretion
  • Stimulates insulin release
  • Supports glucose regulation
  • Reduces appetite
  • Improves gut microbiota balance and gene expression

It also helps regulate liver function, especially hepatic gluconeogenesis, making it highly effective for managing body fat and insulin sensitivity.


Gardenia Fruit Extract (Gardenia jasminoides Ellis)

Gardenia extract offers dual metabolic benefits:

  • Inhibits pancreatic α-amylase, reducing carb digestion and post-meal glucose spikes [6]
  • Increases GLP-1 levels—more significantly than green tea in comparative studies [7]*

This makes it a key component in MonaLean™ for managing appetite and postprandial blood glucose.


Turmeric Root Extract (Curcuma longa, 95% curcumin)

+ Black Pepper Extract (Piper nigrum, 95% piperine)

Turmeric is known for its anti-inflammatory and antioxidant benefits, particularly in metabolic disorders. Curcumin [8]:

  • Helps reduce diet-induced obesity*
  • Stimulates insulin secretion*
  • Supports anti-inflammatory pathways*

However, curcumin has low bioavailability—solved here by adding black pepper extract, which boosts absorption by up to 2000% [9]. This powerful duo enhances insulin action, inflammation control, and metabolic function.


Fenugreek Seed Extract (Trigonella foenum-graecum)

Fenugreek is traditionally used to support blood sugar balance and weight loss. Benefits [10,11] include:

  • Enhancing GLP-1 signaling via its active compound N55
  • Promoting cravings control and appetite regulation*
  • Improving insulin sensitivity *

Unlike synthetic GLP-1 drugs, N55 works in harmony with your body, avoiding hormonal disruption while amplifying the natural incretin effect.


Ginseng Root Extract (Panax ginseng, 20% ginsenosides)

Used in traditional Chinese medicine, ginseng is known for its anti-obesity and anti-diabetic properties. Ginsenosides [12,13,14] have been shown to:

  • Boost GLP-1 secretion*
  • Stimulate insulin release*
  • Improve blood sugar control and insulin sensitivity *

These effects contribute to more efficient glucose utilization and fat metabolism.


White Kidney Bean Extract (Phaseolus vulgaris)

This ingredient serves as a natural carb blocker, helping reduce the glycemic load of meals [15,16] by:

  • Inhibiting α-amylase enzyme activity
  • Limiting carbohydrate absorption
  • Supporting blood sugar stability and fat loss*

It’s ideal for curbing post-meal sugar spikes and supporting steady energy levels.


Chromium (III)

Chromium is a vital trace mineral for insulin function and glucose metabolism. It plays a role [17,18] in:

  • Reducing fasting blood glucose*
  • Supporting lean muscle mass retention
  • Decreasing body fat*
  • Suppressing appetite and food intake*

This makes chromium an essential micronutrient in any blood sugar or body composition regimen.


💡 Why Choose MonaLean™?

MonaLean™ isn’t just another weight management supplement—it’s a clinically supported metabolic enhancer designed to work with your body’s natural biology.

Formulated with patent-pending GLP-1 signaling technology, MonaLean™ helps:

  • Activate natural GLP-1 hormone production*
  • Improve blood sugar control*
  • Reduce cravings and appetite*
  • Support sustainable fat loss and healthy weight*

📊 Supported by emerging clinical data [19], MonaLean™ is a safe, natural alternative to synthetic GLP-1 chemicals—without the risk of side effects.


Clean Label, Clinical Power

  • 🌱 Plant-based, non-synthetic ingredients
  • 📚 Clinically studied & scientifically validated
  • 🔬 Patent-pending formulation
  • 🌿 Vegan, gluten-free, soy-free, allergen-free, fish-free
  • 🧪 3rd-party tested for purity and potency
  • 🏭 Manufactured in FDA-registered, NSF-certified GMP facilities
  • 🇺🇸 Proudly made in the USA

🌟 Support Your Body’s Natural Metabolism

Whether you're looking to support blood sugar control, reduce cravings, or lose body fat naturally, MonaLean™ delivers a science-backed, safe, and plant-powered solution.


Stay tuned for more insights on GLP-1 science, metabolic health, and smart weight loss strategies—only on the Theramone Health™ blog.


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Scientific and Medical Reference

  1. Therapeutic effect of high-dose green tea extract on weight reduction: A randomized, double-blind, placebo-controlled clinical trial - Clinical Nutrition (clinicalnutritionjournal.com)
  2. Effects of green tea extract on insulin resistance and glucagon-like peptide 1 in patients with type 2 diabetes and lipid abnormalities: a randomized, double-blinded, and placebo-controlled trial - PubMed (nih.gov)
  3. The effect of Berberine on weight loss in order to prevent obesity: A systematic review - ScienceDirect
  4. Restoration of GLP-1 secretion by Berberine is associated with protection of colon enterocytes from mitochondrial overheating in diet-induced obese mice | Nutrition & Diabetes (nature.com)
  5. Berberine protects against diet-induced obesity through regulating metabolic endotoxemia and gut hormone levels - PMC (nih.gov)
  6. Inhibitory effect of a weight-loss Chinese herbal formula RCM-107 on pancreatic α-amylase activity: Enzymatic and in silico approaches | PLOS ONE
  7. IJMS | Free Full-Text | The Effects of a Weight-Loss Herbal Formula RCM-107 and Its Eight Individual Ingredients on Glucagon-Like Peptide-1 Secretion—An In Vitro and In Silico Study (mdpi.com)
  8. Curcumin and Weight Loss: Does It Work? - PMC (nih.gov)
  9. Curcumin: A Review of Its’ Effects on Human Health - PMC (nih.gov)
  10. Revisiting Trigonella foenum-graecum L.: Pharmacology and Therapeutic Potentialities - PMC (nih.gov)
  11. Fenugreek Compound (N55) Lowers Plasma Glucose through the Enhancement of Response of Physiological Glucagon-like peptide-1 | Scientific Reports (nature.com)
  12. Ginsenoside metabolite compound K stimulates glucagon-like peptide-1 secretion in NCI-H716 cells via bile acid receptor activation | Archives of Pharmacal Research (springer.com)
  13. Increased glucagon-like peptide-1 secretion may be involved in antidiabetic effects of ginsenosides in: Journal of Endocrinology Volume 217 Issue 2 (2013) (bioscientifica.com)
  14. Antiobesity and Antihyperglycemic Effects of Ginsenoside Rb1 in Rats - PMC (nih.gov)
  15. Blocking carbohydrate absorption and weight loss: a clinical trial using a proprietary fractionated white bean extract - PubMed (nih.gov)
  16. It’s No Has Bean: A Review of the Effects of White Kidney Bean Extract on Body Composition and Metabolic Health - PMC (nih.gov)
  17. Effects of chromium on body composition and weight loss - PubMed (nih.gov)
  18. Effects of chromium picolinate on food intake and satiety - PubMed (nih.gov)
  19. Effects of a glucagon-like peptide-1 (GLP-1) booster on blood glucose, HbA1c, insulin, and GLP1 levels, body weight and body fat in overweight adult men and women. Han et al., Alpine Biotech Report AB20240102H.